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. 1984 Dec 21:316:487-94.
doi: 10.1016/s0021-9673(00)96176-4.

Screening for new microbial products by high-performance liquid chromatography using a photodiode array detector

H P Fiedler

Screening for new microbial products by high-performance liquid chromatography using a photodiode array detector

H P Fiedler. J Chromatogr. .

Abstract

The screening for new microbial metabolites in culture filtrates from Streptomyces tendae TU 901 by high-performance liquid chromatography using a photodiode array detector resulted in detection of new compounds related to the parent compounds. Six peaks in the elution profiles of different strains could be identified as potential new nikkomycins, a group of nucleoside-peptide antibiotics. Structure elucidation confirmed the assumption for new nikkomycin structures.

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