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. 1976 Oct;67(5):755-62.

Detection of oncornavirus-like particles in normal and tumorigenic rat liver cell cultures

K S Narayan, M A Thompson, T Okigaki
  • PMID: 65305

Detection of oncornavirus-like particles in normal and tumorigenic rat liver cell cultures

K S Narayan et al. Gan. 1976 Oct.

Abstract

Six epithelial cell cultures established from adult Wistar rat liver were examined by electron microscopy for oncornavirus-like particles. Two heteroploid and tumorigenic cultures demonstrated many cells with virus-like particles of type-A and type-C morphology. The remaining four, composed of diploid nontumorigenic cells, demonstrated similar virus-like particles but in few cells and only after bromodeoxyuridine treatment. The virus-like particles in the tumorigenic cultures were identified as a rat type-C virus by serological assays.

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