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. 1984;25(4):504-9.
doi: 10.1186/BF03546918.

Platelet aggregation in dogs after live-virus vaccination

B E Jones

Platelet aggregation in dogs after live-virus vaccination

B E Jones. Acta Vet Scand. 1984.

Abstract
in English, Norwegian

Platelet aggregation induced by ADP was studied in dogs after vaccination with a modified live-virus distemper vaccine. A significant decrease in platelet counts was observed about 1 week after the vaccination. There were no consistent changes in the aggregability of the platelets. In 4 samples the aggregability was significantly increased compared to the prevaccination values. The observed changes will not cause a defective hemostasis in otherwise normal dogs.

ADP-inducerad trombocytaggregation mättes hos hundar efter vaccinering med ett modifierat levande valpsjukevaccin. En signifikant sänkning av antalet trombocyter sågs ungefär en vecka efter vaccineringen. Inga systematiska förändringar sågs av trombocyteraas aggregationsförmåga. I fyra fall sågs en signifikant ökning av aggregationsförmågan jämfört med utgångsvärden före vaccinering. De observe-rade förändringarna efter vaccination kommer inte att ge sämre hemostas hos tidigare friska hundar.

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