G, A and M immunoglobulin levels in the parturients' blood serum, umbilical blood of their neonates, and the amniotic fluid in deliveries of prolonged pregnancies

Abstract

The present experiments were carried out with the aim to determine G, A and M immunoglobulin concentration levels in the blood serum of parturients, umbilical blood of their neonates, and in the amniotic fluid in 17 women with prolonged pregnancies. The diagnosis of prolonged pregnancy was confirmed by the typical after term traits in infants. IgG and IgA were detected in all three environments and the presence of IgM was confirmed in all cases in the blood serum and in 76% of the tested samples of amniotic fluid. IgG concentration in the blood serum of mothers with prolonged pregnancy was lower than in physiological pregnancies. Despite this IgG level in the serum of umbilical blood of the neonates was normal in all cases. The values of IgA and IgM were noted to be normal both in the parturients' blood serum as well as in the umbilical blood. Examination of the amniotic fluid did not reveal significant differences in immunoglobulin levels related to the duration of full term pregnancy compared to prolonged pregnancy.