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. 1984 Apr 15;33(4):429-34.
doi: 10.1002/ijc.2910330402.

Preparation and properties of mouse monoclonal antibody (W14A) to human chorionic gonadotropin

F Searle, C S Partridge, A Kardana, A J Green, R G Buckley, R H Begent, G A Rawlins

Preparation and properties of mouse monoclonal antibody (W14A) to human chorionic gonadotropin

F Searle et al. Int J Cancer. .

Abstract

A mouse monoclonal antibody, W14A, has been prepared which reacts with intact human chorionic gonadotropin and its beta-subunit, showing less than 2% cross-reactivity towards the alpha-subunit and 0.5% cross-reactivity towards the beta-subunit of luteinizing hormone. The reagent is suitable for the radioimmunolocalization of choriocarcinoma and trophoblastic teratoma in humans. A preliminary radioimmunoassay has been developed.

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