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. 1984 Oct;311(5985):438-42.
doi: 10.1038/311438a0.

Differentiation of F9 teratocarcinoma stem cells after transfer of c-fos proto-oncogenes

R Müller, E F Wagner

Differentiation of F9 teratocarcinoma stem cells after transfer of c-fos proto-oncogenes

R Müller et al. Nature. 1984 Oct.

Abstract

Transfer of mouse or human c-fos proto-oncogenes into F9 teratocarcinoma stem cells results in expression of c-fos mRNA and protein. This is accompanied by the appearance of morphologically altered cells which express several specific markers characteristic of differentiated cells, suggesting that c-fos plays a role in cellular differentiation.

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