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. 1984 Aug;26(2):280-2.
doi: 10.1128/AAC.26.2.280.

Enterococcal superinfection and colonization with aztreonam therapy

P H Chandrasekar, B R Smith, J L LeFrock, B Carr

Enterococcal superinfection and colonization with aztreonam therapy

P H Chandrasekar et al. Antimicrob Agents Chemother. 1984 Aug.

Abstract

Patients were given aztreonam (SQ 26,776) parenterally for the treatment of various gram-negative infections. During or shortly after therapy, 8 (17.8%) of 45 patients became infected with or colonized by enterococcus. These eight cases included eight urinary tract isolates; one of these cases subsequently developed bacteremia. Five patients required further antimicrobial therapy directed against enterococcus. Patients receiving aztreonam are at risk for the development of enterococcal superinfection or colonization.

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