[Dynamics of interhemispheric asymmetry in fenamine stereotypy in the cat]

Abstract

Stereotyped behaviour induced by d,1-amphetamine in cats is a stable rhythmical process. Expressed stereotypy is characterized by stabilization of the summate curve of motor activity fluctuations by amplitude and periods with different asynchronous changes in the number of the left and right head turnings. Low-frequency stimulation of the caudate nucleus and administration of neuroleptics (haloperidol and clozapine) facilitate destabilization of the fluctuations curve and synchronize changes in the frequency of the left and the right head turnings. Structural or functional elimination of the ventrolateral part of the caudate nucleus head leads to opposite effects. It is suggested that amphetamine-induced stereotypy may be due to dynamic dissociation in time of activity of nigro-striatal systems of both cerebral hemispheres.