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. 1984 Dec;26(6):941-3.
doi: 10.1128/AAC.26.6.941.

Effect of aztreonam on throat and stool flora of cancer patients

P G Jones, G P Bodey, E A Swabb, B Rosenbaum

Effect of aztreonam on throat and stool flora of cancer patients

P G Jones et al. Antimicrob Agents Chemother. 1984 Dec.

Abstract

Eighteen patients with hematological malignancies received aztreonam in one of two dosing regimens, 1 or 2 g every 8 h for a total of 7 to 9 days. Throat and stool cultures were obtained before and during treatment with aztreonam. Aztreonam had little effect on the predominant throat flora. In contrast, facultatively anaerobic gram-negative bacilli were markedly decreased in stools during the administration of aztreonam. Strict anaerobes in the stool were variably affected by aztreonam.

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