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. 1984 Jan 11;12(1 Pt 1):287-305.
doi: 10.1093/nar/12.1part1.287.

Signal search analysis: a new method to localize and characterize functionally important DNA sequences

P Bucher, B Bryan
Free PMC article

Signal search analysis: a new method to localize and characterize functionally important DNA sequences

P Bucher et al. Nucleic Acids Res. .
Free PMC article

Abstract

The generation of "signal search data" represents a general method of describing the common properties of a set of DNA sequences presumed to be functionally analogous. Besides the detailed description of this method we present two computer programs which use signal search data as input data: One that processes them to a "constraint profile" and another one which lists over-represented "signals" of potential functional relevance. To illustrate the possibilities of our method we have analysed a set of transcription initiation sites of sea urchin histone genes.

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References

    1. Nucleic Acids Res. 1980 Mar 11;8(5):957-77 - PubMed
    1. Nature. 1980 May 15;285(5761):147-51 - PubMed
    1. Proc Natl Acad Sci U S A. 1980 Mar;77(3):1432-6 - PubMed
    1. EMBO J. 1982;1(1):27-33 - PubMed
    1. Proc Natl Acad Sci U S A. 1980 Mar;77(3):1265-9 - PubMed

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