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. 1984 Apr;37(4):309-17.
doi: 10.7164/antibiotics.37.309.

A-16686, a new antibiotic from Actinoplanes. I. Fermentation, isolation and preliminary physico-chemical characteristics

B Cavalleri, H Pagani, G Volpe, E Selva, F Parenti
Free article

A-16686, a new antibiotic from Actinoplanes. I. Fermentation, isolation and preliminary physico-chemical characteristics

B Cavalleri et al. J Antibiot (Tokyo). 1984 Apr.
Free article

Abstract

Actinoplanes sp. ATCC 33076 is a new strain that was found to produce an antibiotic, designated A-16686, which is a complex of three closely-related polypeptides containing chlorinated phenyl moieties and D-mannose. Both the complex and the single fractions possess a good activity against Gram-positive bacteria. A-16686 specifically inhibits the synthesis of the bacterial cell wall.

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