Comparative Study
doi: 10.1089/jir.1984.4.609.
Novel human leukocyte interferon subtype and structural comparison of alpha interferon genes
- PMID: 6548765
- DOI: 10.1089/jir.1984.4.609
Item in Clipboard
Comparative Study
Novel human leukocyte interferon subtype and structural comparison of alpha interferon genes
J Interferon Res.
1984 Fall.
Abstract
In the cDNA library of virus-induced human leukocytes a novel subtype of IFN-alpha gene has been identified and sequenced, named IFN-alpha-N. A comparison of nucleotide sequences within the genes coding for different subtypes of human leukocyte interferon (IFN-alpha) has revealed the natural hybrid structure of individual alpha-IFNs-H,B,F, and N. Certain regions of the genes for IFN-alpha-H,B,F,N show a homology with one of the two structurally distinct groups of leukocyte interferons--either IFN-alpha-A,D or IFN-alpha-C,C1 utilized as reference standards.
Similar articles
-
A novel class of human type I interferons.Nucleic Acids Res. 1985 Jul 11;13(13):4739-49. doi: 10.1093/nar/13.13.4739. Nucleic Acids Res. 1985. PMID: 3895159 Free PMC article.
-
Structure and expression of human IFN-alpha genes.Philos Trans R Soc Lond B Biol Sci. 1982 Sep 24;299(1094):7-28. doi: 10.1098/rstb.1982.0102. Philos Trans R Soc Lond B Biol Sci. 1982. PMID: 6128751 Review.
-
The genes for the trophoblast interferons and the related interferon-alpha II possess distinct 5'-promoter and 3'-flanking sequences.J Biol Chem. 1991 Feb 15;266(5):3060-7. J Biol Chem. 1991. PMID: 1704373
-
Efficient expression in Escherichia coli of two species of human interferon-alpha and their hybrid molecules.DNA. 1985 Jun;4(3):221-32. doi: 10.1089/dna.1985.4.221. DNA. 1985. PMID: 3891272
-
Human interferon omega--a review.Mult Scler. 1995;1 Suppl 1:S44-7. Mult Scler. 1995. PMID: 9345398 Review.
Cited by
-
A few distinct 'molecular sandwiches' are basis for structural and functional similarities of subspecies of interferon alpha and of families of growth-promoting hormones.Mol Biol Rep. 1986;11(1):37-42. doi: 10.1007/BF00417593. Mol Biol Rep. 1986. PMID: 3511360
-
A novel class of human type I interferons.Nucleic Acids Res. 1985 Jul 11;13(13):4739-49. doi: 10.1093/nar/13.13.4739. Nucleic Acids Res. 1985. PMID: 3895159 Free PMC article.
-
A sequence-based identification of the genes detected by probesets on the Affymetrix U133 plus 2.0 array.Nucleic Acids Res. 2005 Feb 18;33(3):e31. doi: 10.1093/nar/gni027. Nucleic Acids Res. 2005. PMID: 15722477 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Other Literature Sources
Medical
Molecular Biology Databases
Research Materials