Properdin factor B (Bf) polymorphism: subtyping of SS phenotypes
- PMID: 6554234
- DOI: 10.1007/BF00327124
Properdin factor B (Bf) polymorphism: subtyping of SS phenotypes
Abstract
The authors have studied the genetic polymorphism of the properdin factor B (Bf) by the isoelectrofocusing technique. The SS phenotypes, all similar on agarose gel electrophoresis, were shown to be heterogeneous after isoelectrofocusing; this heterogeneity corresponds to the expression of two new suballeles SA and SB, inherited in a codominant manner. Gene frequencies for 121 individuals with SS phenotype are 0.57 for SA, and 0.43 for SB.
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