A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B
- PMID: 6559257
- DOI: 10.1038/307237a0
A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B
Abstract
Four human complement genes, which have previously been mapped between HLA-D and HLA-B on chromosome 6, have now been aligned on a 98-kilobase (kb) section of the chromosome on the basis of four overlapping cosmid clones of genomic DNA. The C2 and factor B genes, less than 2 kb apart, are about 30 kb from two C4 genes separated from each other by about 10 kb.
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