The preparation of liposomes bearing human (HLA) transplantation antigens
- PMID: 656061
- PMCID: PMC1183984
- DOI: 10.1042/bj1710505
The preparation of liposomes bearing human (HLA) transplantation antigens
Abstract
The incorporation of HLA antigens into liposomes is described. At and above the lipidphase-transition temperature, between 50 and 80% of the added antigenic activity may be incorporated into liposomes in the form of multilamellar vesicles. The antigen appears to be asymmetrically orientated with respect to the lipid bilayer.
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