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Clinical Trial
. 1978 Mar;5(3):223-6.
doi: 10.1111/j.1365-2125.1978.tb01628.x.

Standardized stress and hypertension: comparison of effect of propranolol and methyldopa

F G Dunn, D I Melville, J V Jones, A R Lorimer, T D Lawrie
Clinical Trial

Standardized stress and hypertension: comparison of effect of propranolol and methyldopa

F G Dunn et al. Br J Clin Pharmacol. 1978 Mar.

Abstract

1 Using a standardized form of mental stress, 21 patients with idiopathic hypertension were investigated before and after treatment with placebo (n=8), propranolol (n=7) or methyldopa (n=6). 2 Blood pressure was satisfactorily controlled in the propranolol and methyldopa groups but only the propranolol group showed modification of the pressor response to stress testing. 3 These results suggest that propranolol may provide more uniform control of blood pressure than methyldopa in patients with essential hypertension.

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