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. 1984;17(2):90-4.
doi: 10.1007/BF00200042.

Augmentation of antitumor resistance by a strain of unicellular green algae, Chlorella vulgaris

K Tanaka, F Konishi, K Himeno, K Taniguchi, K Nomoto

Augmentation of antitumor resistance by a strain of unicellular green algae, Chlorella vulgaris

K Tanaka et al. Cancer Immunol Immunother. 1984.

Abstract

Growth of Meth-A tumor in CDF1 mice was inhibited significantly by injection of a hot water extract of a strain of Chlorella vulgaris (CE) into the tumor or into the subcutaneous tissue near the tumor. The augmentation of resistance by CE may require the participation of T cells and macrophages, since it was abolished or reduced in athymic nude mice or mice treated with carrageenan, a macrophage blocker. Mice treated with CE exhibited antigen-specific augmented resistance against rechallenge with tumor. Moreover, the antitumor effect of CE was comparable with that of Corynebacterium parvum, but its mechanism of effect might be different.

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References

    1. Azuma I, Taniyama T, Yamawaki M, Sugimura K, Yamamura Y. Adjuvant and antitumor activities or Nocardia cell-wall skeletons. Gann. 1976;67:733. - PubMed
    1. Azuma I, Yamawaki M, Yasumoto K, Yamamura Y. Antitumor activity of Nocardia cell wall skeleton preparations in transplantable tumors in syngeneic mice and patients with malignant pleurisy. Cancer Immunol Immunother. 1978;4:95. doi: 10.1007/BF00200109. - DOI
    1. Baldwin RW, Pimm MV. BCG in tumor immunotherapy. Adv Cancer Res. 1978;28:91. doi: 10.1016/S0065-230X(08)60647-8. - DOI - PubMed
    1. Barot-Ciorbaru R, Petit JF, Chassoux D, Salomon JC. Antitumor activity of intralesionally administered Nocardia opaca preparations in rat and mouse tumors: a comparison with BCG and Corynebacterium parvum . Int J Immunopharmacol. 1981;3:115. doi: 10.1016/0192-0561(81)90001-1. - DOI - PubMed
    1. Catanzaro PJ, Schwartz JH, Graham RC. Spectrum and possible mechanism of carrageenan cytotoxicity. Am J Pathol. 1971;64:387. - PMC - PubMed

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