[Changes in the indicators of the fibrinolytic and kallikrein-kinin systems in patients with calculous pyelonephritis]

Abstract

A total of 48 patients with calculous pyelonephritis were examined before and after surgery. A study was made of the fibrinolytic system (according to the status of XIIa kallikrein-dependent fibrinolysis, lysis of the plasma clots and euglobulin lysis) and of the kallikrein-kinin system of the plasma (according to kallikrein activity, kininogen content, kininase activity, spontaneous esterase activity and prekallikrein content). The patients with calculos pyelonephritis demonstrated KKS activation and fibrinolysis reduction related to both the lowering of the activator levels and elevation of antiplasmin levels, which in turn created the risk of thrombophilia in this group of patients.