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. 1983 Feb 11;219(4585):666-71.
doi: 10.1126/science.6572017.

Protein engineering

K M Ulmer

Protein engineering

K M Ulmer. Science. .

Abstract

The prospects for protein engineering, including the roles of x-ray crystallography, chemical synthesis of DNA, and computer modelling of protein structure and folding, are discussed. It is now possible to attempt to modify many different properties of proteins by combining information on crystal structure and protein chemistry with artificial gene synthesis. Such techniques offer the potential for altering protein structure and function in ways not possible by any other method.

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