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. 1983 Feb;6(2):75-7.
doi: 10.1016/0198-8859(83)90063-0.

Epidemic and endemic HLA-B and DR associations in mucocutaneous lymph node syndrome

A M Krensky, S Grady, K M Shanley, W Berenberg, E J Yunis

Epidemic and endemic HLA-B and DR associations in mucocutaneous lymph node syndrome

A M Krensky et al. Hum Immunol. 1983 Feb.

Abstract

HLA-A,B and DR antigens were evaluated in 51 patients with mucocutaneous lymph node syndrome (Kawasaki disease) during both endemic and epidemic periods in the Boston area. Although 80% of patients were HLA-B5 (70% HLA-Bw51) during endemic periods, there were no HLA-B5 individuals during the epidemic period. There was, however, an increased incidence of HLA-Bw44 during the Boston epidemic. Such different associations in endemic versus epidemic periods suggest possible different, as yet unknown, inciting agents.

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