doi: 10.1073/pnas.80.7.2067.
Complete mRNA coding sequence of the acetylcholine binding alpha-subunit of Torpedo marmorata acetylcholine receptor: a model for the transmembrane organization of the polypeptide chain
- PMID: 6572962
- PMCID: PMC393754
- DOI: 10.1073/pnas.80.7.2067
Item in Clipboard
Complete mRNA coding sequence of the acetylcholine binding alpha-subunit of Torpedo marmorata acetylcholine receptor: a model for the transmembrane organization of the polypeptide chain
Proc Natl Acad Sci U S A.
1983 Apr.
Abstract
A 1,350-base-pair-long cDNA clone, named p alpha-2, was isolated by hybridization to the previously characterized clone p alpha-1 and found to be specific for the alpha-subunit of the Torpedo marmorata acetylcholine receptor. The nucleotide sequences of both cDNA inserts were analyzed and the sequence of the complete coding region and part of the 5' and 3' untranslated regions of the alpha-chain mRNA was determined. The complete amino acid sequence of the alpha-chain precursor is presented and used to develop a model for the transmembrane organization of the polypeptide.
Similar articles
-
Identification of a cDNA clone coding for the acetylcholine binding subunit of Torpedo marmorata acetylcholine receptor.EMBO J. 1982;1(6):713-7. doi: 10.1002/j.1460-2075.1982.tb01235.x. EMBO J. 1982. PMID: 6897919 Free PMC article.
-
Isolation and characterization of a cDNA clone for the complete protein coding region of the delta subunit of the mouse acetylcholine receptor.Proc Natl Acad Sci U S A. 1984 Dec;81(24):7970-4. doi: 10.1073/pnas.81.24.7970. Proc Natl Acad Sci U S A. 1984. PMID: 6096870 Free PMC article.
-
Molecular genetics of Torpedo marmorata acetylcholine receptor.Adv Exp Med Biol. 1984;181:17-29. doi: 10.1007/978-1-4684-4868-9_3. Adv Exp Med Biol. 1984. PMID: 6549423 No abstract available.
-
Postsynapic membrane of Torpedo electroplax: acetylcholine receptor localization and its use as a tool in the study of cellular immuninty in myasthenia gravis.Adv Cytopharmacol. 1979;3:255-67. Adv Cytopharmacol. 1979. PMID: 382788 Review. No abstract available.
-
Localization of the functional sites on the alpha chain of acetylcholine receptor.Fed Proc. 1987 Jun;46(8):2538-47. Fed Proc. 1987. PMID: 2439384 Review.
Cited by
-
Antibodies to synthetic peptides as probes for the binding site on the alpha subunit of the acetylcholine receptor.Proc Natl Acad Sci U S A. 1985 May;82(10):3490-3. doi: 10.1073/pnas.82.10.3490. Proc Natl Acad Sci U S A. 1985. PMID: 2582416 Free PMC article.
-
Expression of fusion proteins of the nicotinic acetylcholine receptor from mammalian muscle identifies the membrane-spanning regions in the alpha and delta subunits.J Cell Biol. 1992 Jan;116(2):385-93. doi: 10.1083/jcb.116.2.385. J Cell Biol. 1992. PMID: 1730761 Free PMC article.
-
Complete nucleotide sequence of Torpedo marmorata mRNA coding for the 43,000-dalton nu 2 protein: muscle-specific creatine kinase.Proc Natl Acad Sci U S A. 1984 Dec;81(23):7313-7. doi: 10.1073/pnas.81.23.7313. Proc Natl Acad Sci U S A. 1984. PMID: 6095285 Free PMC article.
-
Amphipathic analysis and possible formation of the ion channel in an acetylcholine receptor.Proc Natl Acad Sci U S A. 1984 Jan;81(1):155-9. doi: 10.1073/pnas.81.1.155. Proc Natl Acad Sci U S A. 1984. PMID: 6320162 Free PMC article.
-
A single gene codes for the nicotinic acetylcholine receptor alpha-subunit in Torpedo marmorata: structural and developmental implications.EMBO J. 1984 Jan;3(1):35-41. doi: 10.1002/j.1460-2075.1984.tb01758.x. EMBO J. 1984. PMID: 6323168 Free PMC article.
References
Publication types
MeSH terms
Substances
Associated data
- Actions
- Actions
LinkOut - more resources
Full Text Sources
Other Literature Sources
