doi: 10.1128/AAC.23.3.509.
Antimycoplasmal activity of ofloxacin (DL-8280)
- PMID: 6573869
- PMCID: PMC184683
- DOI: 10.1128/AAC.23.3.509
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Antimycoplasmal activity of ofloxacin (DL-8280)
Antimicrob Agents Chemother.
1983 Mar.
Abstract
Ofloxacin (DL-8280; (+/-)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1- pipera-zinyl)-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid) showed a broader spectrum and a greater potency of antimycoplasmal activity than did pipemidic acid, norfloxacin, tetracyclines, and lincomycin, but was inferior to erythromycin. Its mycoplasmacidal potency against clinical isolates of Mycoplasma pneumoniae was also greater than that of other quinolones and tetracyclines.
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