A useful method for predicting creatinine clearance in children
- PMID: 657498
Item in Clipboard
A useful method for predicting creatinine clearance in children
Clin Chem.
1978 Jul.
Abstract
A practical method for predicting creatinine clearance for pediatric patients from serum creatinine concentration and patient age is presented. Creatinine excretion rate (ER) can be predicted from the patient's age, in years, by the formula: ER = (0.035 X age) + 0.236. Using the predicted excretion rate and serum creatinine concentration, creatinine clearance can be predicted. There was good correlation (r = 0.90) between predicted and observed creatinine clearances in 101 subjects with various degrees of renal impairment. This method allows renal function to be rapidly estimated.
Similar articles
-
[Evaluation of creatinine clearance in pediatric patients, excluding determination of creatininuria].Quad Sclavo Diagn. 1980 Dec;16(4):437-50. Quad Sclavo Diagn. 1980. PMID: 7244114 Italian.
-
[Measurement of renal function in children].Arch Pediatr. 1994 Mar;1(3):273-80. Arch Pediatr. 1994. PMID: 7994337 French.
-
Serum creatinine level and renal function in children.Am J Dis Child. 1992 Oct;146(10):1232-5. doi: 10.1001/archpedi.1992.02160220118036. Am J Dis Child. 1992. PMID: 1415055
-
[Glomerular filtration markers in pediatrics].Rev Med Suisse Romande. 2002 Dec;122(12):625-30. Rev Med Suisse Romande. 2002. PMID: 12611189 Review. French.
-
Estimating renal function in children: a new GFR-model based on serum cystatin C and body cell mass.Dan Med J. 2012 Jul;59(7):B4486. Dan Med J. 2012. PMID: 22759853 Review.
Cited by
-
Angiotensin-converting enzyme inhibitor nephrotoxicity in neonates with cardiac disease.Pediatr Cardiol. 2014 Mar;35(3):499-506. doi: 10.1007/s00246-013-0813-2. Pediatr Cardiol. 2014. PMID: 24233240
-
Clinical Pharmacokinetics of Vancomycin in Critically Ill Children.Eur J Drug Metab Pharmacokinet. 2019 Dec;44(6):807-816. doi: 10.1007/s13318-019-00568-6. Eur J Drug Metab Pharmacokinet. 2019. PMID: 31301023
-
Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children.Clin Pharmacokinet. 2006;45(9):931-56. doi: 10.2165/00003088-200645090-00005. Clin Pharmacokinet. 2006. PMID: 16928154
-
Vancomycin population pharmacokinetics analysis in Chinese paediatric patients with varying degrees of renal function and ages: development of new practical dosing recommendations.J Antimicrob Chemother. 2023 Aug 2;78(8):2037-2051. doi: 10.1093/jac/dkad202. J Antimicrob Chemother. 2023. PMID: 37379498 Free PMC article.
-
Renal Function Outcomes of High-risk Neuroblastoma Patients Undergoing Radiation Therapy.Int J Radiat Oncol Biol Phys. 2017 Oct 1;99(2):486-493. doi: 10.1016/j.ijrobp.2017.04.003. Epub 2017 Apr 11. Int J Radiat Oncol Biol Phys. 2017. PMID: 28872000 Free PMC article.