Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1983 Jul;80(14):4460-3.
doi: 10.1073/pnas.80.14.4460.

Chromosomal assignment of a family of human oncogenes

J Ryan, P E Barker, K Shimizu, M Wigler, F H Ruddle

Chromosomal assignment of a family of human oncogenes

J Ryan et al. Proc Natl Acad Sci U S A. 1983 Jul.

Abstract

A family of human transforming genes, previously shown to share homology with the ras family of viral oncogenes, maps to three different human chromosomes. A well-characterized mouse-human hybrid cell panel, combined with Southern blotting, was used in this study. The transforming gene of the T24 bladder carcinoma cell line maps to human chromosome 11. An oncogene isolated from the lung carcinoma cell line SK-Calu-1 maps to human chromosome 12. The third ras-related gene, cloned from SK-N-SH, a neuroblastoma cell line, maps to human chromosome 1.

PubMed Disclaimer

References

    1. Cytogenet Cell Genet. 1975;14(3-6):279-81 - PubMed
    1. J Mol Biol. 1975 Nov 5;98(3):503-17 - PubMed
    1. Nature. 1976 Mar 11;260(5547):170-3 - PubMed
    1. Science. 1977 Apr 22;196(4288):390-405 - PubMed
    1. Cancer Res. 1977 May;37(5):1364-71 - PubMed

Publication types

LinkOut - more resources