Neurophysin biosynthesis: conversion of a putative precursor during axonal transport
- PMID: 65791
- DOI: 10.1126/science.65791
Neurophysin biosynthesis: conversion of a putative precursor during axonal transport
Abstract
[35S]Cysteine injected adjacent to the supraoptic nucleus of the rat is rapidly incorporated into a 20,000-dalton protein that, in time, is converted to a 12,000-dalton labeled protein, neurophysin. This putative precursor of neurophysin appears to be synthesized in the supraoptic nucleus and transformed to neurophysin and related peptides during axonal transport to the neurohypophysis.
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