Gastrin stimulated H+ secretion in amphibian gastric mucosa: effect of tetrodotoxin
- PMID: 658248
- DOI: 10.1007/BF01936999
Gastrin stimulated H+ secretion in amphibian gastric mucosa: effect of tetrodotoxin
Abstract
The role of neural mechanisms in gastrin stimulated H+ secretion was studied using amphibian gastric fundic mucosa. Spontaneously secreting mucosae were converted to resting state (zero H+ secretory rate) using Burimamide. Following removal of burimamide, 3 X 10(-6) M tetrodotoxin did not block gastrin stimulation of H+ secretion indicating that neural mechanisms are not required.
Similar articles
-
The effects of burimamide and metiamide on gastric secretion in the conscious cat.Agents Actions. 1974 Dec;4(5):311-3. doi: 10.1007/BF01964932. Agents Actions. 1974. PMID: 4463719 No abstract available.
-
Effect of burimamide and metiamide on pentagastrin-stimulated gastric acid secretion and gastric mucosal blood flow in cats.Experientia. 1974 Dec 15;30(12):1435-7. doi: 10.1007/BF01919682. Experientia. 1974. PMID: 4155372 No abstract available.
-
Acid secretion and intracellular pH in isolated oxyntic cells.J Membr Biol. 1978 Jan 12;38(1-2):31-50. doi: 10.1007/BF01875161. J Membr Biol. 1978. PMID: 24120
-
Secretory state of gastric mucosa and resistance to injury by exogenous acid.Am J Surg. 1977 Jan;133(1):81-5. doi: 10.1016/0002-9610(77)90198-2. Am J Surg. 1977. PMID: 13668
-
Characteristics and tachyphylaxis of gastrin-stimulated gastric acid secretion in the cat.J Physiol. 1978 Mar;276:1-11. doi: 10.1113/jphysiol.1978.sp012216. J Physiol. 1978. PMID: 650426 Free PMC article.