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. 1978 May 15;34(5):625-6.
doi: 10.1007/BF01936999.

Gastrin stimulated H+ secretion in amphibian gastric mucosa: effect of tetrodotoxin

J G Spenney

Gastrin stimulated H+ secretion in amphibian gastric mucosa: effect of tetrodotoxin

J G Spenney. Experientia. .

Abstract

The role of neural mechanisms in gastrin stimulated H+ secretion was studied using amphibian gastric fundic mucosa. Spontaneously secreting mucosae were converted to resting state (zero H+ secretory rate) using Burimamide. Following removal of burimamide, 3 X 10(-6) M tetrodotoxin did not block gastrin stimulation of H+ secretion indicating that neural mechanisms are not required.

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