doi: 10.1007/BF01937009.
Effect of variations in temperature on antimuscarinic activity in guinea-pig atria
- PMID: 658257
- DOI: 10.1007/BF01937009
Item in Clipboard
Effect of variations in temperature on antimuscarinic activity in guinea-pig atria
Experientia.
.
Abstract
The characteristics of the antimuscarinic activity of homatropine, gallamine and stercuronium in guinea-pig atria remained constant over the temperature range 22--37 degrees C in that a linear Arunlakshana-Schild plot was obtained with homatropine and nonlinear plots occurred with gallamine or stercuronium. A trend towards higher dose-ratios with reduction in temperature was only significant for gallamine.
Similar articles
-
The selective antimuscarinic action of stercuronium.Br J Pharmacol. 1980 Oct;70(2):313-21. doi: 10.1111/j.1476-5381.1980.tb07938.x. Br J Pharmacol. 1980. PMID: 6893558 Free PMC article.
-
Antimuscarinic action of methoctramine, a new cardioselective M-2 muscarinic receptor antagonist, alone and in combination with atropine and gallamine.Eur J Pharmacol. 1987 Dec 1;144(2):117-24. doi: 10.1016/0014-2999(87)90509-7. Eur J Pharmacol. 1987. PMID: 3436364
-
The interaction of nicotinic receptor antagonists at muscarinic receptors.Clin Exp Pharmacol Physiol. 1987 May;14(5):385-91. doi: 10.1111/j.1440-1681.1987.tb00988.x. Clin Exp Pharmacol Physiol. 1987. PMID: 3677483
-
The cardio-selectivity of himbacine: a muscarine receptor antagonist.Naunyn Schmiedebergs Arch Pharmacol. 1986 Jan;332(1):16-20. doi: 10.1007/BF00633191. Naunyn Schmiedebergs Arch Pharmacol. 1986. PMID: 3951563
-
C14-aminosteroid LNF 209, an agent with positive inotropic and antimuscarinic activity.J Cardiovasc Pharmacol. 1992;20(5):807-12. J Cardiovasc Pharmacol. 1992. PMID: 1280745
Cited by
-
The selective antimuscarinic action of stercuronium.Br J Pharmacol. 1980 Oct;70(2):313-21. doi: 10.1111/j.1476-5381.1980.tb07938.x. Br J Pharmacol. 1980. PMID: 6893558 Free PMC article.