doi: 10.1007/BF01937023.
Effects of oestrogen and progesterone on rat pineal N-acetyl transferase activity and melatonin production
- PMID: 658265
- DOI: 10.1007/BF01937023
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Effects of oestrogen and progesterone on rat pineal N-acetyl transferase activity and melatonin production
Experientia.
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Abstract
We have extended previous studies on pineal beta-receptors to include effects of oestradiol or PMSG treatment in the immature female rat. Neither manipulation has any effect on norepinephrine-induced N-acetyl transferase (NAT) activity in vitro. In the adult ovariectomised rat oestrogen/progesterone priming exerts a small sensitising effect to beta-stimulation with isoproterenol. Progesterone alone, in vitro, inhibits the release of melatonin from pineals of adult ovariectomised rats.
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