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. 1978 May 15;34(5):667-9.
doi: 10.1007/BF01937023.

Effects of oestrogen and progesterone on rat pineal N-acetyl transferase activity and melatonin production

M Wilkinson, J Arendt

Effects of oestrogen and progesterone on rat pineal N-acetyl transferase activity and melatonin production

M Wilkinson et al. Experientia. .

Abstract

We have extended previous studies on pineal beta-receptors to include effects of oestradiol or PMSG treatment in the immature female rat. Neither manipulation has any effect on norepinephrine-induced N-acetyl transferase (NAT) activity in vitro. In the adult ovariectomised rat oestrogen/progesterone priming exerts a small sensitising effect to beta-stimulation with isoproterenol. Progesterone alone, in vitro, inhibits the release of melatonin from pineals of adult ovariectomised rats.

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References

    1. Endocrinology. 1970 Sep;87(3):527-33 - PubMed
    1. Endocrinol Exp. 1975 Jun;9(2):141-8 - PubMed
    1. Life Sci. 1975 Oct 15;17(8):1227-32 - PubMed
    1. Nature. 1975 Oct 2;257(5525):404-5 - PubMed
    1. Gen Comp Endocrinol. 1975 May;26(1):50-8 - PubMed