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. 1984 Jan;39(1):19-22.
doi: 10.1136/thx.39.1.19.

HLA associations in sarcoidosis: a study of two ethnic groups

J Gardner, H G Kennedy, A Hamblin, E Jones

HLA associations in sarcoidosis: a study of two ethnic groups

J Gardner et al. Thorax. 1984 Jan.

Abstract

We report results of HLA-A, B, C, and DR typing in groups of white Caucasians of English descent and black West Indians of African descent with sarcoidosis. In the English patients we found a significantly increased frequency of Cw7, which was not found in the West Indian patients. Our results also suggest that DR3 and, in particular, inheritance of the B8/Cw7/DR3 haplotype is associated with good prognosis in English patients with sarcoidosis. There was no association between any HLA antigen and prognosis in the West Indian patients in this study.

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References

    1. Tissue Antigens. 1973;3(2):95-8 - PubMed
    1. Nature. 1976 Aug 26;262(5571):795-7 - PubMed
    1. Scand J Immunol. 1978;8(1):63-73 - PubMed
    1. J Immunol. 1980 Sep;125(3):1071-7 - PubMed
    1. N Engl J Med. 1981 Jan 22;304(4):185-92 - PubMed