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. 1984;12(2):131-3.
doi: 10.1007/BF00254605.

Modification of oral methotrexate absorption in children with leukemia

M J Mahony, M S Murphy, J Wadsworth, M G Mott

Modification of oral methotrexate absorption in children with leukemia

M J Mahony et al. Cancer Chemother Pharmacol. 1984.

Abstract

The effect of administering oral methotrexate in different formulations to children with acute lymphoblastic leukemia was evaluated. Methotrexate tablets alone achieved higher mean plasma levels and larger area under the absorption curve than either methotrexate liquid alone or methotrexate tablets taken concurrently with metoclopramide.

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References

    1. Cancer Chemother Pharmacol. 1979;3(2):117-20 - PubMed
    1. Lancet. 1980 Nov 1;2(8201):944-6 - PubMed
    1. Br Med J. 1977 Dec 10;2(6101):1511-2 - PubMed
    1. Br J Cancer. 1982 Feb;45(2):300-3 - PubMed
    1. Cancer Treat Rep. 1981;65 Suppl 1:77-81 - PubMed

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