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. 1984 Apr;11(4):399-404.
doi: 10.1016/0165-4608(84)90020-7.

A high-resolution study of chromosome changes in a human prostatic carcinoma cell line (LNCaP)

Z Gibas, R Becher, E Kawinski, J Horoszewicz, A A Sandberg

A high-resolution study of chromosome changes in a human prostatic carcinoma cell line (LNCaP)

Z Gibas et al. Cancer Genet Cytogenet. 1984 Apr.

Abstract

A high-resolution study of chromosomal rearrangements in a human prostatic cancer cell line, LNCaP, has been performed. The cytogenetic analysis revealed a pseudodiploid karyotype and the presence of seven marker chromosomes resulting from five aberrational events. The analysis of four clones derived from the original line showed a near-tetraploid chromosome number and the presence of the same seven markers observed in the original line. This is the first complete description of karyotypic rearrangements in a prostatic cancer cell line.

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