Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1984 Jul;10(4):369-76.
doi: 10.1007/BF01535632.

Chromosomal assignments of human genes for serine proteases trypsin, chymotrypsin B, and elastase

N K Honey, A Y Sakaguchi, C Quinto, R J MacDonald, G I Bell, C Craik, W J Rutter, S L Naylor

Chromosomal assignments of human genes for serine proteases trypsin, chymotrypsin B, and elastase

N K Honey et al. Somat Cell Mol Genet. 1984 Jul.

Abstract

The genes for the serine proteases trypsin, chymotrypsin B, and elastase were chromosomally assigned in man using cDNA probes that have been isolated from a rat pancreatic cDNA library. DNA from human X rodent somatic cell hybrids was cleaved with BamHI or EcoRI and analyzed by Southern filter hybridization methods for the segregation of the genes for trypsin-1 (TRY1), chymotrypsin B (CTRB), and elastase-1 (ELA1). TRY1 was assigned to human chromosome 7q22----qter, CTRB to chromosome 16, and ELA1 to chromosome 12. Although the three genes are members of the same gene family, they are dispersed over different chromosomes.

PubMed Disclaimer

Publication types

LinkOut - more resources