Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1978 Jun 1;153(1):203-9.
doi: 10.1016/s0021-9673(00)89873-8.

Rapid and sensitive method for determination of haloperidol in human samples using nitrogen-phosphorus selective detection

G Bianchetti, P L Morselli

Rapid and sensitive method for determination of haloperidol in human samples using nitrogen-phosphorus selective detection

G Bianchetti et al. J Chromatogr. .

Abstract

A sensitive gas-chromatographic method for quantitative analysis of haloperidol in human plasma is described. The use of nitrogen-phosphorus selective detection reduces the time required for analysis. Azaperone is used as the internal reference standard. The method is suitable for the determination of haloperidol plasma levels in patients treated with doses ranging from 1.2 to 200 mg/day. No interference from drugs needed in the associated antipsychotic therapy has been found. The simplicity, specificity and sensitivity of the method make it suitable for routine analysis of haloperidol plasma levels in psychotic patients undergoing chronic treatment.

PubMed Disclaimer