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Case Reports
. 1984 Dec;59(12):1187-9.
doi: 10.1136/adc.59.12.1187.

Placental steroid sulphatase deficiency

A A Attenburrow, M Heslip, M J Henderson, J B Holton, I V Scott, L J Arthur
Case Reports

Placental steroid sulphatase deficiency

A A Attenburrow et al. Arch Dis Child. 1984 Dec.

Abstract

Low maternal plasma and urinary oestrogen concentrations in pregnancy are usually indicative of fetal problems, either placental insufficiency or fetal adrenal hypoplasia. Paediatricians, however, should follow obstetricians in becoming increasingly aware that deficiency of placental steroid sulphatase activity, a condition related to X linked ichthyosis, may produce the same abnormalities.

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References

    1. Pediatr Res. 1977 Aug;11(8):894-7 - PubMed
    1. J Inherit Metab Dis. 1982;5(3):164-76 - PubMed
    1. J Clin Invest. 1981 Dec;68(6):1404-10 - PubMed

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