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. 1983 Dec;1(1):29-37.
doi: 10.1093/oxfordjournals.molbev.a040304.

Structure and evolution of human and African ape rDNA pseudogenes

E Brownell  1 , M Krystal, N Arnheim
Affiliations

Structure and evolution of human and African ape rDNA pseudogenes

E Brownell et al. Mol Biol Evol. 1983 Dec.

Abstract

We discuss the evolutionary significance of four aberrant 18S rDNA clones that were obtained from human, chimpanzee, and gorilla DNA libraries. We show that these clones carry representatives of a small 18S rDNA pseudogene family that arose in a common ancestor of these species. Aspects of their structure and phylogenetic distribution suggest that the 18S pseudogenes no longer interact genetically with normal ribosomal genes and therefore may not be linked to nucleolus organizer regions.

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