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. 1983 Jul 15;39(7):755-6.
doi: 10.1007/BF01990310.

Dantrolene: evidence for effects on Na permeability properties of the nodal membrane

Dantrolene: evidence for effects on Na permeability properties of the nodal membrane

J R Schwarz et al. Experientia. .

Abstract

The effects of dantrolene on myelinated frog nerve fibers were studied in voltage clamp experiments. Dantrolene shifted the potential-dependent parameters describing Na+ permeability towards more negative membrane potentials. The findings are interpreted as a change in the negative surface charge of the membrane.

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