Dantrolene: evidence for effects on Na permeability properties of the nodal membrane
- PMID: 6602716
- DOI: 10.1007/BF01990310
Dantrolene: evidence for effects on Na permeability properties of the nodal membrane
Abstract
The effects of dantrolene on myelinated frog nerve fibers were studied in voltage clamp experiments. Dantrolene shifted the potential-dependent parameters describing Na+ permeability towards more negative membrane potentials. The findings are interpreted as a change in the negative surface charge of the membrane.