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. 1983 Aug;96(8):73-5.

[Stimulation of DNA synthesis in guinea pig spleen lymphocytes by staphylococcal peptidoglycan]

[Article in Russian]
V V Khorobrykh, V K Pozur
  • PMID: 6603876

[Stimulation of DNA synthesis in guinea pig spleen lymphocytes by staphylococcal peptidoglycan]

[Article in Russian]
V V Khorobrykh et al. Biull Eksp Biol Med. 1983 Aug.

Abstract

The mode of action of peptidoglycan on DNA synthesis in spleen lymphocytes of intact guinea-pigs was studied. It was found that peptidoglycan isolated from Staphylococcus aureus 2287 is mainly mitogenic for B lymphocytes that have IgG receptors on their surface. In contrast to lipopolysaccharide from Salmonella typhimurium, it seems that peptidoglycan is also mitogenic for less differentiated B cells.

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