doi: 10.1128/AAC.23.6.938.
Mechanism of resistance to some cephalosporins in Staphylococcus aureus
- PMID: 6604497
- PMCID: PMC185012
- DOI: 10.1128/AAC.23.6.938
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Mechanism of resistance to some cephalosporins in Staphylococcus aureus
Antimicrob Agents Chemother.
1983 Jun.
Abstract
The mechanism of resistance to some cephalosporins in Staphylococcus aureus strains was investigated with high-pressure liquid chromatography and nuclear magnetic resonance spectrometry. Drug inactivation by penicillinase was found to be the main mechanism of resistance to cefazolin, cephaloridine, and cephalothin in S. aureus.
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