[Effect of BCG (Bacillus Calmette Guérin) sensitization on the generation of tumor specific killer T cells]
[Article in
Japanese]
- PMID: 6604499
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[Effect of BCG (Bacillus Calmette Guérin) sensitization on the generation of tumor specific killer T cells]
[Article in
Japanese]
Gan To Kagaku Ryoho.
1983 Sep.
Abstract
Effector cells of augmented resistance against a syngeneic MC-1 tumor in C57BL/6 mice sensitized with BCG were determined by Winn test, and the following results were obtained: Sensitization of mice with BCG (1.0 mg/mouse) augmented resistance against primary and secondary inoculation of MC-1 tumor. Peritoneal exudate cells of tumor-bearing mice showed a growth-inhibitory activity against MC-1 tumor in Winn test. Sensitization with BCG augmented such an activity of PEC. Augmented resistance was ascribed to a plastic dish-nonadherent, nylon wool column-nonadherent and Thy 1.2-positive cells.
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