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. 1983 Sep;46(9):832-6.
doi: 10.1136/jnnp.46.9.832.

Specific involvement of peripheral T lymphocytes against acetylcholine receptors in myasthenia gravis

B M Conti-Tronconi, A Scotti, A Sghirlanzoni, F Clementi

Specific involvement of peripheral T lymphocytes against acetylcholine receptors in myasthenia gravis

B M Conti-Tronconi et al. J Neurol Neurosurg Psychiatry. 1983 Sep.

Abstract

A specific sensitisation of blood T lymphocytes against the nicotinic acetylcholine receptor has been demonstrated in myasthenic patients. After thymectomy the T lymphocytes response was quickly decreased and in most patients it reached normal values. The T response remained at low or normal levels for at least two years. In patients who had undergone thymectomy three or more years before, a T lymphocyte response against acetylcholine receptors was frequently detected.

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