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Comparative Study
. 1983 Aug;24(2):227-32.
doi: 10.1128/AAC.24.2.227.

In vitro activity and beta-lactamase stability of a monobactam, SQ 26,917, compared with those of aztreonam and other agents

H C Neu, P Labthavikul
Comparative Study

In vitro activity and beta-lactamase stability of a monobactam, SQ 26,917, compared with those of aztreonam and other agents

H C Neu et al. Antimicrob Agents Chemother. 1983 Aug.

Abstract

SQ 26,917 is a monobactam antibiotic. Its in vitro activity was compared with those of aztreonam, cefotaxime, ceftazidime, and moxalactam. SQ 26,917, which contains a beta-methyl configuration on the beta-lactam ring, was similar in activity to aztreonam with the exception of greater activity against Pseudomonas aeruginosa isolates. SQ 26,917 had no activity against gram-positive isolates or anaerobic bacteria. It was not hydrolyzed by common plasmid and chromosomal beta-lactamases.

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References

    1. Antimicrob Agents Chemother. 1976 Sep;10(3):535-42 - PubMed
    1. Adv Microb Physiol. 1973;9:31-88 - PubMed

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