Clinical Trial
doi: 10.1042/cs0660165.
Prostaglandins cause an increase in serum acute-phase proteins in man, which is diminished in systemic sclerosis
- PMID: 6607151
- DOI: 10.1042/cs0660165
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Clinical Trial
Prostaglandins cause an increase in serum acute-phase proteins in man, which is diminished in systemic sclerosis
Clin Sci (Lond).
1984 Feb.
Abstract
The prostaglandin E1 increases the plasma concentration of acute-phase proteins in man and decreases the concentration of certain carrier proteins. This response is greatly diminished in patients with systemic sclerosis, a chronic inflammatory disease leading to fibrosis. These findings pose new questions about the mediation of the acute-phase response and its role in controlling the inflammatory process.
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