Gonococcal ophthalmia neonatorum: the case for prophylaxis in tropical Africa
- PMID: 6609023
- PMCID: PMC2536272
Gonococcal ophthalmia neonatorum: the case for prophylaxis in tropical Africa
Abstract
PIP: During a period when silver nitrate prophylaxis against ophthalmia neonatorum was discontinued in the maternity ward of the Yaounde Central Hospital, a study was begun of the prevalence of gonorrheal infection among women and their newborns. Strains of oxidase-positive gonococci were isolated on modified Thayer-Martin agar from vaginal pool specimens of 40 (14%) of the 296 women studied and from the conjunctiva of 12 (4%) of their 297 liveborn children. The risk of transmission from and infected mother to her child was 30%. No specific symptoms of infection were observed by the mothers with positive cultures at the time of delivery, though 14 of them gave a history of having received treatment for a vaginal infection during pregnancy. Younger, low parity womenwere at a higher risk of infection. Since gonococcal ophthalmia neonatorum is a preventable cause of blindness, the increasing incidence of gonorrheal infection in Africa calls for an urgent reexamination of policies for the prevention of this infection among African women and their newborn children, the majority of whom are born without antenatal care or a trained birth attendant. (author's modified)
Similar articles
-
Epidemiology and control of gonococcal ophthalmia neonatorum.Bull World Health Organ. 1989;67(5):471-7. Bull World Health Organ. 1989. PMID: 2611972 Free PMC article.
-
Prophylaxis of gonococcal and chlamydial ophthalmia neonatorum. A comparison of silver nitrate and tetracycline.N Engl J Med. 1988 Mar 17;318(11):653-7. doi: 10.1056/NEJM198803173181101. N Engl J Med. 1988. PMID: 3278234 Clinical Trial.
-
Gonococcal ophthalmia neonatorum. Relationship of maternal factors and delivery room practices to effective control measures.Am J Obstet Gynecol. 1975 Jul 1;122(5):589-92. Am J Obstet Gynecol. 1975. PMID: 807108
-
Specific prophylaxis of gonorrheal ophthalmia neonatorum. A review.N Engl J Med. 1966 Mar 31;274(13):731-4. doi: 10.1056/NEJM196603312741308. N Engl J Med. 1966. PMID: 5325447 Review. No abstract available.
-
Neonatal and childhood gonococcal infections.Clin Obstet Gynecol. 1975 Mar;18(1):143-51. doi: 10.1097/00003081-197503000-00013. Clin Obstet Gynecol. 1975. PMID: 1091381 Review.
Cited by
-
Sexually transmitted pathogens in pregnant women in a rural South African community.Genitourin Med. 1989 Aug;65(4):276-80. doi: 10.1136/sti.65.4.276. Genitourin Med. 1989. PMID: 2807289 Free PMC article.
-
Acceptability, feasibility, equity and resource use for prenatal screening for chlamydia and gonorrhea: A systematic review.Can Commun Dis Rep. 2024 Jul 24;50(7-8):250-258. doi: 10.14745/ccdr.v50i78a03. eCollection 2024 Jul-Aug. Can Commun Dis Rep. 2024. PMID: 39170589 Free PMC article.
-
Reducing perinatal infection risk in newborns of mothers who received inadequate prenatal care.Paediatr Child Health. 2023 Jul 22;28(5):307-323. doi: 10.1093/pch/pxad014. eCollection 2023 Aug. Paediatr Child Health. 2023. PMID: 37484040 Free PMC article. Review.
-
Keeping an Eye on Chlamydia and Gonorrhea Conjunctivitis in Infants in the United States, 2010-2015.Sex Transm Dis. 2017 Jun;44(6):356-358. doi: 10.1097/OLQ.0000000000000613. Sex Transm Dis. 2017. PMID: 28499285 Free PMC article.
-
La réduction du risque d'infection périnatale chez les nouveau-nés de mères dont les soins prénatals étaient inappropriés.Paediatr Child Health. 2023 Jul 22;28(5):307-323. doi: 10.1093/pch/pxad015. eCollection 2023 Aug. Paediatr Child Health. 2023. PMID: 37484035 Free PMC article. Review.
References
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical