Comparative Study
doi: 10.1007/BF00273003.
Comparison of expression of the fragile site at Xq27 in T and B lymphocytes
- PMID: 6611290
- DOI: 10.1007/BF00273003
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Comparative Study
Comparison of expression of the fragile site at Xq27 in T and B lymphocytes
Hum Genet.
1984.
Abstract
We compared the fragile X (fraX) expression in T and B lymphocytes from four hemizygous males with fraX. Blood cultures were stimulated with a T cell mitogen (phytohemagglutinin:PHA) and with a B cell mitogen (pokeweed mitogen:PWM). A significant decrease in fraX expression was observed in cultures stimulated with PWM when compared to PHA-stimulated ones.
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