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Case Reports
. 1983 May;16(2):92-9.

Immunopathological diagnosis of plasma-cell dyscrasia. Part II. "Secondary" monoclonal gammopathy

H F Tien, T S Huang, S W How, C Y Chuang, I S Meisha
  • PMID: 6617316
Case Reports

Immunopathological diagnosis of plasma-cell dyscrasia. Part II. "Secondary" monoclonal gammopathy

H F Tien et al. Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi. 1983 May.

Abstract

Two cases of secondary plasma-cell dyscrasia are presented: one is of undetermined cause and the other is due to hepatic schistosomiasis. Both of the patients showed a prominent IgG monoclonal spikes of more than 3000 mg/dl. One of them had multiple osteolytic bone lesions and pathological fractures, and histopathological picture showed a chronic inflammatory process. An additional case of marked polyclonal gammopathy due to schistosomiasis is also presented to illustrate the immunochemical differential between the physiological and altered immune responses. Schistosomiasis is postulated to be an important immunopathological cause of plasma-cell dyscrasia.

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