Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1983;15(9):1169-73.
doi: 10.1016/0020-711x(83)90233-1.

The effect of phospholipid bilayers on AMP-deaminase from rat tissues

E Prus, M Zydowo
Comparative Study

The effect of phospholipid bilayers on AMP-deaminase from rat tissues

E Prus et al. Int J Biochem. 1983.

Abstract

The ATP-activated adenylate deaminase (EC 3.5.4.6) from the rat heart, kidney, spleen, liver and brain showed a mixed-type allosteric activation under the influence of phosphatidylcholine-containing liposomes, but no effect was observed on the non-activated enzyme isolated from all these tissues but the brain. The brain enzyme was activated by the liposomes also in the absence of ATP. No effect of the phosphatidylcholine-containing liposomes could be shown on the adenylate deaminase isolated from skeletal muscle and red blood cells. The phosphatidate-containing liposomes exerted an inhibitory effect on the enzyme isolated from the heart, kidney and brain, being without effect on the enzyme from skeletal muscle.

PubMed Disclaimer

Publication types