Scanning electron microscopic (SEM) studies on the effect of x-ray contrast media on aortic endothelium in the rat
- PMID: 6618829
- DOI: 10.1097/00004424-198307000-00017
Scanning electron microscopic (SEM) studies on the effect of x-ray contrast media on aortic endothelium in the rat
Abstract
A study comparing the effects of diatrizoate, ioxitalamate, metrizamide, ioxaglate, and a 22% sorbitol on aortic endothelia of the rat was performed. In each case 1 ml of the respective solution was injected in a single dose into the aorta. Endothelial damage was seen after injection of metrizamide, diatrizoate, and ioxitalamate. After injection of ioxaglate or sorbitol, only minor endothelial changes were observed.
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